How are permanent specimens typically sent to pathology?

Permanent specimens are typically sent to pathology in a solution of 10% formalin. This formalin solution preserves the tissue and prevents autolysis and putrefaction, which would compromise the integrity of the specimen and the accuracy of the histological examination. The preservation allows pathologists to examine the cellular architecture and make accurate diagnoses through microscopic evaluation.

Other methods of handling specimens, such as sending them dry, without a solution, or on a sponge, do not provide the necessary preservation required for pathology. Dry specimens can deteriorate quickly, leading to loss of cellular details. Specimens sent without a solution lack the necessary preservation to maintain tissue viability. While sending on a sponge can offer some physical support, without proper storage in a fixative like 10% formalin, the tissue would not remain in a state suitable for analysis. Thus, sending specimens in 10% formalin is the standard procedure that ensures optimal preservation for accurate pathological assessment.