The congenital defect spina bifida primarily affects which part of the body?

Spina bifida is a congenital defect that primarily affects the spine. It occurs when the neural tube, which develops into the spine and surrounding structures, does not close completely during early fetal development. This incomplete closure can result in the spinal cord and nerves being exposed or protruding through the openings in the vertebrae, leading to a variety of physical and neurological challenges. The defect can manifest in different forms, such as spina bifida occulta, meningocele, or myelomeningocele, each presenting varying degrees of severity and implications for mobility and function. Understanding that spina bifida is specifically related to the spine helps clarify the significance of neural tube defects in terms of broader implications for neurological and physical health.